U.S. Federal Route 150 runs east-west across Central Floyd County. It runs from the Floyd/Harrison County Line to the Indiana/Kentucky State Line. U.S. Rt. 150 passes through the following towns in Floyd County. Greenville Galena New Albany
U.S. Rt. 150 is multi-plexed in Floyd County. Interstate 64, from near Floyds Knobs to the Indiana/Kentucky State Line.
A BGS on WB I-64/U.S. Rt. 150/IN St Rt 62. A BGS on WB I-64/U.S. Rt. 150/IN St Rt 62. WB I-64/IN St Rt 62 at west U.S. Rt. 150. WB I-64/U.S. Rt. 150 at I-265. WB I-64/U.S. Rt. 150 east of I-265. A BGS on NB IN St Rt 111. A guide marker on NB IN St Rt 111. EB I-64/U.S. Rt. 150 in New Albany. EB I-64/U.S. Rt. 150 near the Ohio River. WB I-64/U.S. Rt. 150 at the Indiana Welcome Sign. EB I-64/U.S. Rt. 150 at the Ohio River. WB I-64/U.S. Rt. 150 at the Ohio River. WB I-64/U.S. Rt. 150 at the Ohio River.