U.S. Rt. 41 is the main north-south route through Central Gibson County. Many of the smaller access roads in this county connect to U.S. Rt. 41. U.S. Rt. 41 passes through the following town in Gibson County. Patoka U.S. Rt. 41 is not multi-plexed in Gibson County. U.S. Rt. 41 intersects the following highways in Gibson County. Indiana State Route 56, near Hazleton.
The Knox/Gibson County Line is at the Richard L. Mc Connell Bridge over the White River. SB U.S. Rt. 41 crossing the above bridge. SB U.S. Rt. 41 near Hazelton. NB U.S. Rt. 41 north of IN St Rt 56. NB U.S. Rt. 41 south of IN St Rt 56. NB U.S. Rt. 41 near the Patoka River. NB U.S. Rt. 41 near County Road 100N. NB U.S. Rt. 41 north of IN St Rt 64. NB U.S. Rt. 41 at IN St Rt 64. A sign to take away some confusion on which route 64 is where. SB U.S. Rt. 41 near IN St Rt 64 at Princeton. A BGS on EB IN St Rt 64/NB IN St Rt 65. NB U.S. Rt. 41 south of IN St Rt 64. NB U.S. Rt. 41 north of County Road 300S. NB U.S. Rt. 41 at County Road 300S. NB U.S. Rt. 41 near County Road 550S. NB U.S. Rt. 41 at IN St Rt 168. NB U.S. Rt. 41 at IN St Rt 168. NB U.S. Rt. 41 south of IN St Rt 168. NB U.S. Rt. 41 north of County Road 925S. A mile marker in the median. SB U.S. Rt. 41 near I-64. NB U.S. Rt. 41 north of County Road 1250S. NB U.S. Rt. 41 south of County Road 1250S. SB U.S. Rt. 41 at I-64. The Gibson/Vanderburgh County Line is just past the I-64 overpass. A BGS on EB I-64. NB U.S. Rt. 41 at the Vanderburg/Gibson County Line.
