Iowa State Route 22 is one of the main east-west surface routes in central Muscatine County. East of the City of Muscatine, this proviedes a nice drive along the banks of the Mississippi River. IA St Rt 22 passes through the following towns in Muscatine County. Nichols Muscatine
Fairport Montpelier IA St Rt 22 is multi-plexed in Muscatine County. Iowa State Route 70, near Nichols.
Looking west along IA St Rt 22 near the Cedar River. Junction sign on NB U.S. Rt. 61 at Muscatine. NB U.S. Rt. 61/EB IA St Rt 22 on the northwest side of Muscatine. NB U.S. Rt. 61/EB IA St Rt 22 on the northside of Muscatine. A junction marker on SB U.S. Rt. 61. SB BUSN U.S. Rt. 61/IA St Rt 38; EB IA St Rt 22 in Muscatine.
