U.S. Federal Route 61 from Muscatine to the Scott/Muscatine County line ia mostly a four-lane divided highway. South of Muscatine is become a two-lane surface route. At Muscatine, U.S. Rt. 61 by-passes the town to the north and west. U.S. Rt. 61 passes through the following town in Muscatine County. Muscatine
U.S. Rt. 61 is multi-plexed in Muscatine County. Iowa State Route 22, around Muscatine.
Branches of U.S. Rt. 61 in Muscatine County. NB U.S. Rt. 61/EB IA St Rt 92 on the southside of Muscatine. SB U.S. Rt. 61 south of IA St Rt 22. NB U.S. Rt. 61 on the westside of Muscatine. NB U.S. Rt. 61/EB IA St Rt 22 on the northwest side of Muscatine. NB U.S. Rt. 61/EB IA St Rt 22 on the northside of Muscatine. NB U.S. Rt. 61 north of Muscatine. NB U.S. Rt. 61 near Fairport. NB U.S. Rt. 61 near Blue Grass.