U.S. Federal Route 20 runs east-west across Central Dubuque County. It is a multi-lane highway across the county, except at the Mississippi River crossing. U.S. Rt. 20 passes through the following town in Dubuque County. Dyersville
Farley
Epworth Dubuque
U.S. Rt. 20 is multi-plexed in Dubuque County. U.S. Rt. 52, from Dubuque to Dyersville.
Iowa State Route 946, at Dubuque. U.S. Rt. 61, at Dubuque. (NO Direct Interchange) U.S. Rt. 151, at Dubuque. (NO Direct Interchange)
A junction marker on SB U.S. Rt. 52. WB U.S. Rt. 20/NB U.S. Rt. 52 at Dyersville. WB U.S. Rt. 20/NB U.S. Rt. 52 at Farley. WB U.S. Rt. 20/NB U.S. Rt. 52 at DCH Y13. WB U.S. Rt. 20/NB U.S. Rt. 52 east of Farley. WB U.S. Rt. 20/NB U.S. Rt. 52 west of Epworth. WB U.S. Rt. 20/NB U.S. Rt. 52 west of DCH Y21. WB U.S. Rt. 20/NB U.S. Rt. 52 west of east U.S. Rt. 52. A junction marker on NB U.S. Rt. 52. A guide marker on NB U.S. Rt. 52. A guide marker on NB U.S. Rt. 52. WB U.S. Rt. 20 at east U.S. Rt. 52. EB U.S. Rt. 20 at Old Highway Road. EB U.S. Rt. 20 at Middle Fork Catfish Creek. EB U.S. Rt. 20 in Dubuque. EB U.S. Rt. 20 at Center Fork Catfish Creek. EB U.S. Rt. 20 at Gandolfo Street. EB U.S. Rt. 20 at Fremont Ave. WB U.S. Rt. 20 west of Locust Street. A BGS on NB U.S. Rt. 52/61/151. EB U.S. Rt. 20 west of Locust Street. EB U.S. Rt. 20 at Locust Street. A guide marker in Dubuque. A BGS on Locust Street. A BGS on SB U.S. Rt. 61/151. A BGS on SB U.S. Rt. 61/151. The Mississippi River Bridge on U.S. Rt. 20 as seen from NB U.S. Rt. 52/61/151. EB U.S. Rt. 20 on the Iowa side of the birdge. EB U.S. Rt. 20 at the main truss. EB U.S. Rt. 20 in the main arch of the bridge. EB U.S. Rt. 20 near the Illinois State Line. WB U.S. Rt. 20 crossing the Mississippi River. WB U.S. Rt. 20 crossing the Mississippi River. WB U.S. Rt. 20 at the Iowa Welcome Sign. (October, 2021) WB U.S. Rt. 20 at the Iowa Welcome Sign. (August, 2024)