U.S. Federal Route 61 is a north-south highway in Central Clinton County. From the Clinton/Scott County Line to near De Witt, it runs along a expressway. Then from near De Witt to Iowa State Route 136 is a multi-lane highway. From Iowa State Route 136 to the Clinton/Jackson County Line it is a expressway again. U.S. Rt. 61 passes through the following town in Clinton County. De Witt
Welton U.S. Rt. 61 is multi-plexed in Clinton County. U.S. Rt. 30, near De Witt.
U.S. Rt. 61 intersects the following highways in Clinton County. U.S. Rt. 30, near De Witt.
NB U.S. Rt. 61 at the Clinton/Scott County Line. SB U.S. Rt. 61 south of U.S. Rt. 30. NB U.S. Rt. 61 at the interchange with east U.S. Rt. 30. A BGS on WB U.S. Rt. 30. A BGS on WB U.S. Rt. 30. WB U.S. Rt. 30/NB U.S. Rt. 61 south of west U.S. Rt. 30. WB U.S. Rt. 30/NB U.S. Rt. 61 near De Witt. A BGS on EB U.S. Rt. 30. NB U.S. Rt. 61 near De Witt. NB U.S. Rt. 61 near Welton.