U.S. Federal Route 69 runs north-south in Warren County. It runs from the Polk/Warren County Line, at Metro-Des Moines to the Clarke/Warren County Line, near New Virginia. U.S. Rt. 69 passes through the following towns in Warren County. Des Moines
Indianola
U.S. Rt. 69 is multi-plexed in Warren County. U.S. Rt. 65, from Des Moines to near Indianola.
U.S. Rt. 69 intersects the following highways in Warren County. U.S. Rt. 65, at Des Moines. Iowa State Route 5, at Des Moines.