Kentucky State Route 225 is a north-south highway in Southern Knox County. It runs from U.S. Rt. 25E/Kentucky Secondary State Route 3439, at Barbourville to the Knox/Bell County Line, near Wheeler. KY St Rt 225 passes through the following towns in Knox County. Barbourville
Artemus Trosper Kayjay Wheeler KY St Rt 225 is not multi-plexed in Knox County. KY St Rt 225 intersects the following highways in Knox County. U.S. Rt. 25E, at Barbourville. Kentucky Secondary State Route 3439, at Barbourville. Kentucky Secondary State Route 2421, at Barbourville. Kentucky State Route 930, at Atremus.
A junction marker on NB U.S. Rt. 25E. A guide marker on NB U.S. Rt. 25E.
