Kentucky State Route 80 is an east-west highway in Calloway County. It runs from the Calloway/Graves County Line, near Farmington, to the Calloway/Marshall County Line, near Aurora. KY St Rt 80 passes through the following towns in Calloway County. Coldwater Murray Van Cleave KY St Rt 80 is not multi-plexed in Calloway County. KY St Rt 80 intersects the following highways in Calloway County. Kentucky Secondary State Route 1836, near Coldwater. Kentucky State Route 299, near Murray. Kentucky State Route 783, near Murray. U.S. Rt. 641, at Murray. Kentucky Secondary State Route 1483, near Murray. Kentucky State Route 94C, near Almo. Kentucky State Route 464, near Shiloh. Kentucky Secondary State Route 1551, near Shiloh. Kentucky Secondary State Route 1346, near Shiloh.