U.S. Federal Route 641 runs north-south in Central Calloway County. It runs from the Kentucky/Tennessee State Line, at Hazel, to the Calloway/Marshall County Line, near Hardin. U.S. Rt. 641 passes through the following towns in Calloway County. Hazel
Branches of U.S. Rt. 641 in Calloway County. NB U.S. Rt. 641 at the Kentucky Welcome Sign. NB U.S. Rt. 641 in Hazel. NB U.S. Rt. 641 in Calloway Street in Hazel. NB U.S. Rt. 641 near Miller Street in Hazel. NB U.S. Rt. 641 south of Green Plain Road. NB U.S. Rt. 641 south of Murray.