Kentucky State Route 821 is a short east-west highway in Central Calloway. It runs along Sycamore Street in Murray. It goes from U.S. Rt. 641/Kentucky State Route 121, west to 16th Street. KY St Rt 821 passes through the following town in Calloway County. Murray KY St Rt 121 is not multi-plexed in Calloway County. KY St Rt 821 intersects the following highways in Calloway County. U.S. Rt. 641, at Murray. Kentucky State Route 121, at Murray.
A junction marker on NB U.S. Rt. 641/KY St Rt 121.