U.S. Federal Route 25W runs north-south in Central Whitley County. It runs from The Laurel/Whitley County Line, near North Corbin, to the Kentucky/Tennessee State Line, near Jellico, Tennessee. U.S. Rt. 25W passes through the following highways in Whitley County. Corbin
Goldbug Williamsburg Pleasant View Saxton U.S. Rt. 25W is multi-plexed in Whitley County. Kentucky State Route 312, at Corbin.
SB U.S. Rt. 25W at the Laurel/Whitley County Line. NB U.S. Rt. 25W north of east KY St Rt 312. A junction marker on SB U.S. Rt. 25W. A guide marker on SB U.S. Rt. 25W. SB U.S. Rt. 25W near Lake Ave. SB U.S. Rt. 25W at KY Sec St Rt 3041. A BGS on SB I-75. A BGS on SB I-75. A BGS on SB I-75. A BGS on SB I-75. A BGS on SB I-75. SB U.S. Rt. 25W at I-75 north of Williamsburg. SB U.S. Rt. 25W south of I-75 north of Williamsburg. SB U.S. Rt. 25W north of Williamsburg. SB U.S. Rt. 25W north of KY St Rt 26. SB U.S. Rt. 25W at KY St Rt 296.