Maryland State Route 66 is a north-south highway in Eastern Washington County. This runs from ALT U.S. Rt. 40 near Boonsboro, to Maryland State Route 64, near Smithsburg. MD St Rt 66 passes through the following towns in Washington County. Wagners Crossroads Beaver Creek Cavetown Smithsburg MD St Rt 66 is not multi-plexed in Washington County. MD St Rt 66 intersects the following highways in Washington County. ALT U.S. Rt. 40, near Boonsboro. U.S. Rt. 40, at Wagerns Crossroads. Interstate 70, near Beaver Creek. Maryland State Route 64, near Cavetown. Maryland State Route 64, near Smithburg.