Michigan State Route 40 is the main north-south highway in Eastern Cass County. This runs from the Cass/Van Buren County Line to U.S. Rt. 12, near Mottville. MI St Rt 40 passes through the following towns in Cass County. Marcellus
MI St Rt 40 is not multi-plexed in Cass County. MI St Rt 40 intersects the following highways in Cass County. Michigan State Route 216, at Marcellus.