Missouri Secondary State Route E is a north-south highway in Pike County. It runs from U.S. Rt. 54/Missouri Secondary State Route M, at Curryville, to Missouri Secondary State Route C, near Frankford. MO Sec St Rt E passes through the following town in Pike County. Curryville
MO Sec St Rt E is not multi-plexed in Pike County. MO Sec St Rt E intersects the following highways in Pike County. U.S. Rt. 54, at Curryville. Missouri Secondary State Route M, at Curryville.