Missouri State Route 224 runs east-west in Central and Northwestern Lafayette County. It connects to U.S. Rt. 24 at each end. MO St Rt 224 passes through the following towns in Lafayette County. Lexington Wellington
Missouri Secondary State Route D, near Napoleon. U.S. Rt. 24, near Napoleon.
A BGS on SB MO St Rt 13. A BGS on SB MO St Rt 13. WB MO St Rt 224/SB BUSN MO St Rt 13 in Lexington. WB MO St Rt 224 in Lexington. A junction marker on NB MO St Rt 131. WB MO St Rt 224 in Wellington.