Missouri State Route 6 is one of three east-west highways in Knox County. This highway runs across the central part of the county, and is one of two highways to run from each county line to the other. MO St Rt 6 passes through the following towns in Knox County. Knox City Edina
MO St Rt 15 intersects the following highways in Knox County. Missouri Secondary State Route E, at Knox City. Missouri Secondary State Route V, at Knox City. Missouri Secondary State Route T, near Edina. Missouri State Route 15, at Edina.
EB MO St Rt 6 in Edina. A junction marker on SB MO St Rt 15. WB MO St Rt 6/SB MO St Rt 15 in Edina. WB MO St Rt 6 west of Edina. EB MO St Rt 6 at the Knox/Adair County Line.
