U.S. Federal Route 412 is a main east-west highway across the county. East of Interstate 55, this highway runs along the Interstate 155 expressway. This is also the areas only Mississippi River crossings. U.S. Rt. 412 passes through the following town in Pemiscot County. Hayti U.S. Rt. 412 is multi-plexed in Pemiscot County. Missouri State Route 84, from the Dunklin/Pemiscot County Line to Hayti. Interstate 155, from Interstate 55 to the Missouri/Tennessee State Line.
EB I-155/U.S. Rt. 412, east of I-55/U.S. Rt. 61. EB I-155/U.S. Rt. 412, near MO St Rt 84/MO Sec St Rt U. EB I-155/U.S. Rt. 412 near M.P. 6. EB I-155/U.S. Rt. 412 near the Mississippi River. River marker, minus a "p" on EB I-155/U.S. Rt. 412. EB I-155/U.S. Rt. 412 at the Mississippi River. EB I-155/U.S. Rt. 412 crossing the Mississippi River.