U.S. Federal Route 50 is an east-west highway in Northern Cole County. It runs from the Cole/Moniteau County Line to the Cole/Osage County Line, via Jefferson City. U.S. Rt. 50 passes through the following towns in Cole County. Saint Martins Jefferson City
U.S. Rt. 50 is multi-plexed in Cole County. U.S. Rt. 63, from Jefferson City to the Cole/Osage County Line.
BUSN U.S. Rt. 50, at Jefferson City. Missouri Secondary State Route J, near Schubert. Missouri Secondary State Route M, near Schubert.
Branches of U.S. Rt. 50 in Cole County. A BGS in Jefferson City. WB U.S. Rt. 50/NB U.S. Rt. 63 near Nelson Drive in Jefferson City. A BGS in Jefferson City. WB U.S. Rt. 50/SB U.S. Rt. 63 near Lafayette in Jefferson City. WB U.S. Rt. 50 at U.S. Rt. 54/63. A BGS on EB U.S. Rt. 54. EB U.S. Rt. 50 at U.S. Rt. 54/63. A BGS on WB U.S. Rt. 54/SB U.S. Rt. 63. A BGS on SB U.S. Rt. 63. EB U.S. Rt. 50 near Dix Rd. WB U.S. Rt. 50 near Dix Rd. A BGS on NB MO St Rt 179. A BGS on SB MO St Rt 179. EB U.S. Rt. 50 near BUSN U.S. Rt. 50/MO St Rt 179. A junction marker on SB MO Sec St Rt T. EB U.S. Rt. 50 near St. Martins. EB U.S. Rt. 50 near Centertown.
