U.S. Federal Route 61 is a north-south highway in Clark County. This is the northern most county in Missouri that it passes through. From the Clark/Lewis County Line, near Saint Patrick, to Missouri State Route 27, south of Wayland, it is a four-lane highway. From Missouri State Route 27 to the Iowa/Missouri State Line it is a two lane highway. U.S. Rt. 61 passes through the following town in Clark County. Alexandria
U.S. Rt. 61 is multi-plexed in Clark County. U.S. Rt. 136, from near Alexandria to the Iowa/Missouri State Line.
NB U.S. Rt. 61 at the Clark/Lewis County Line. NB U.S. Rt. 61 near Gregory Landing. A BGS on NB U.S. Rt. 61. NB U.S. Rt. 61 near MO St Rt 27. NB U.S. Rt. 61 at MO St Rt 27. U.S. Rt. 61 heads up the ramp on the right. A BGS on EB U.S. Rt. 136. A junction marker on EB U.S. Rt. 136. NB U.S. Rt. 61/EB U.S. Rt. 136 near Alexandria. NB U.S. Rt. 61/EB U.S. Rt. 136 near the Iowa/Missouri State Line. NB U.S. Rt. 61/EB U.S. Rt. 136 near the Iowa/Missouri State Line.
