U.S. Federal Route 65 runs north-south in Saline County. It enters Saline County, near Longwood, and heads north to Marshall. This highway enters Lafayette County, near Grand Pass. From the Pettis/Saline County Line to Marshall it is a four-lane highway. U.S. Rt. 65 passes through the following towns in Saline County. Marshall
Malta Bend
Grand Pass
U.S. Rt. 65 is not multi-plexed in Saline County. U.S. Rt. 65 intersects the following highways in Saline County. Interstate 70, near Longwood. U.S. Rt. 40, near Longwood. Missouri Secondary State Route UU, near Napton. Missouri Secondary State Route H, near Napton. BUSN U.S. Rt. 65, at Marshall. Missouri Secondary State Route YY, at Marshall.
Branches of U.S. Rt. 65 in Saline County. A BGS on EB I-70/U.S. Rt. 40. NB U.S. Rt. 65 on the southwest side of Marshall. NB U.S. Rt. 65 near MO Sec St Rt N. NB U.S. Rt. 65 near Malta Bend. NB U.S. Rt. 65 near Grand Pass. NB U.S. Rt. 65 west of Grand Pass. NB U.S. Rt. 65 near the Lafayette/Saline County Line.