New York State Route 263 is a north-south highway in Erie County. It runs north of the Buffalo Metro Area. NY St Rt 263 passes through the following towns in Erie County. Amherst NY St Rt 263 is not multi-plexed in Erie County. NY St Rt 263 intersects the following highways in Erie County. U.S. Rt. 62, at Amherst. New York State Route 324, at Amherst. Interstate 290, at Amherst. New York State Route 270, at Amherst. Interstate 990, at Amherst. New York State Route 78, at Amherst.
