U.S. Federal Route 25 runs north-south through the Hendersonville Area. It runs from U.S. Rt. 25/176, near East Flat Rock, to Interstate 26; U.S. Rt. 25/74, near Fletcher. BUSN U.S. Rt. 25 passes through the following towns in Henderson County. East Flat Rock Hendersonville Balfour Mountain Home Naples BUSN U.S. Rt. 25 is not multi-plexed in Henderson County. BUSN U.S. Rt. 25 intersects the following highways in Henderson County. U.S. Rt. 25, near East Flat Rock. U.S. Rt. 176, near East Flat Rock. North Carolina State Route 225, at Hendersonville. U.S. Rt. 64, at Hendersonville.