U.S. Federal Route 20 is an east-west highway in Northern Lake County. It runs between Ohio State Route 2 and Interstate 90. U.S. Rt 20 passes through the following towns in Lake County. Mapledale Willoughby Mentor Painesville U.S. Rt. 20 is not multi-plexed in Lake County. U.S. Rt. 20 intersects the following highways in Lake County. Interstate 90, at Mapledale. Ohio State Route 91, at Willoughby. Ohio State Route 306, at Mentor. Ohio State Route 44, at Mentor. Ohio State Route 2, at Mentor. Ohio State Route 528, near Madison.