U.S. Federal Route 22, Muskingum County, Ohio

Roads of the Mid-South & West > Highways of the State of Ohio > U.S. Federal Route 22, Ohio > U.S. Federal Route 22; Muskingum County, Ohio

U.S. Federal Route 22
Muskingum County

U.S. Federal Route 22 is a east-west highway in Central Muskingum County. It runs from the Perry/Muskingum County Line, near Mt. Perry, to the Muskingum/Guernsey County Line, near New Concord.

U.S. Rt. 22 passes through the following towns in Muskingum County.
East Fultonham
White Cottage
South Zanesville
Zanesville

Pleasant Grove
Norwich
New Concord

U.S. Rt. 22 is multi-plexed in Muskingum County.
Ohio State Route 93, from near White Cottage, to near Pleasant Grove.
U.S. Rt. 40, from Zanesville to the Muskingum/Guernsey County Line.

Ohio State Route 60, at Zanesville.
Ohio State Route 146, at Zanesville.

U.S. Rt. 22 intersects the following highways in Muskingum County.
Ohio State Route 345, at East Fultonham.
Ohio State Route 93, near White Cottage.
Ohio State Route 719, at South Zanesville.
U.S. Rt. 40, at Zanesville.
Ohio State Route 60, at Zanesville.
Ohio State Route 146, at Zanesville.
Ohio State Route 60, at Zanesville.
Ohio State Route 146, at Zanesville.
Ohio State Route 93, at Pleasant Grove.

Interstate 70, near Norwich.
Ohio State Route 83, at New Concord.

WB U.S. Rt. 22/40; SB OH St Rt 93 near Green Street in Zanesville.

WB U.S. Rt. 22/40; SB OH St Rt 93 near Briarcliff Drive.

WB U.S. Rt. 22/40; SB OH St Rt 93, near Eastwood Drive.

A guide marker near Zanesville.

A BGS on WB I-70.

2 January 2026