Pennsylvania State Route 16 runs east-west across East-Central Fulton County. It runs from the Franklin/Fulton County Line, northwest of Cove Gap, to McConnellsburg. PA St Rt 16 passes through the following town in Fulton County. McConnellsburg PA St Rt 16 is not multi-plexed in Fulton County. PA St Rt 16 intersects the following highways in Fulton County. U.S. Rt. 522, at McConnellsburg.
WB PA St Rt 16 at the Franklin/Fulton County Line.