Roads of the Mid-South & West > Highways of the Commonwealth of Pennsylvania > U.S. Federal Route 422, Pennsylvania, > U.S. Federal Route 422; Lebanon County, Pennsylvania

U.S. Federal Route 422 Lebanon County

U.S. Federal Route 422 is an east-west highway in Central Lebanon County. It runs from the Berks/Lebanon County Line, near Myerstown, to the Lebanon/Dauphin County Line, near Palmyra.

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U.S. Rt. 422 passes through the following towns in Lebanon County.
Myerstown
Lebanon
Cleona
Annville
Palmyra

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U.S. Rt. 422 is not multi-plexed in Lebanon County.

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U.S. Rt. 422 intersects the following highways in Lebanon County.
Pennsylvania State Route 501, at Myerstown.
Pennsylvania State Route 645, at Myerstown.
Pennsylvania State Route 897, at Lebanon.

Pennsylvania State Route 72, at Lebanon.

Pennsylvania State Route 934, at Annville.
Pennsylvania State Route 117, at Palmyra.

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WB U.S. Rt. 422 east of Myerstown.

WB U.S. Rt. 422 west of Dutchway Drive.

WB U.S. Rt. 422 at PA St Rt 501.

WB U.S. Rt. 422 west of PA St Rt 501.

WB U.S. Rt. 422 near Fairlane Ave.

WB U.S. Rt. 422 east of Lebanon.

WB U.S. Rt. 422 at 15th Ave.

WB U.S. Rt. 422 west of 8th Ave.

WB U.S. Rt. 422 east of PA St Rt 897.

WB U.S. Rt. 422 at Lincoln.

WB U.S. Rt. 422 near 25th St.

WB U.S. Rt. 422 at Cyrus St.

A junction marker in Cleona.

WB U.S. Rt. 422 near Center St.

WB U.S. Rt. 422 near Weaber St.

WB U.S. Rt. 422 east of PA St Rt 934.

WB U.S. Rt. 422 at PA St Rt 934.

WB U.S. Rt. 422 west of PA St Rt 934.

WB U.S. Rt. 422 near Quittapahilla River.

WB U.S. Rt. 422 west of Annville.

WB U.S. Rt. 422 near Apple Blossom Lane.

WB U.S. Rt. 422 near Congress Ave.

WB U.S. Rt. 422 at PA St Rt 117.

WB U.S. Rt. 422 east of Railroad Street.

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15 October 2025