South Carolina State Route is a north-south highway around Greenville. It runs from U.S. Rt. 25, near Gantt, to U.S. Rt. 276/SC St Rt 253, at Sans Souci. SC St Rt 291 passes through the following towns in Greenville County. Gantt Greenville
Sans Souci SC St Rt 291 is multi-plexed in Greenville County. South Carolina State Route 253, near Sans Souci. SC St Rt 291 intersects the following highways in Greenville County. U.S. Rt. 25, near Gantt. Interstate 85, at Greenville. U.S. Rt. 276, at Greenville. Interstate 385, at Greenville. Connector U.S. Rt. 29, at Greenville. U.S. Rt. 29, at Greenville. South Carolina State Route 253, near Sans Souci. U.S. Rt. 276, at Sans Souci. South Carolina State Route 253, at Sans Souci.
A BGS on NB I-85. A BGS on NB I-85. A BGS on NB I-85. A BGS on NB I-85. A BGS on NB I-385. A BGS on NB I-385. A BGS on NB I-385. NB SC St Rt 291 north of I-385. A guide marker on NB SC St Rt 291. A guide marker on NB SC St Rt 291.