Roads of the Mid-South & West > Highways of the Commonwealth of Virginia > Interstate 81, Virginia

Interstate 81

Interstate 81 is a north-south highway in Western Virginia. This is the along the eastside of the Appliantion Mountians. I-81 connects most of the major metropolitian areas in Western Virginia to east other.

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While in Virginia, I-81 is multi-plexed.

I-81 is multi-plexed with...
...U.S. Rt. 58, from Bristol to near Abingdon, M.P. 19.

...U.S. Rt. 52, near Wytheville.

...Interstate 77, near Wytheville.

...U.S. Rt. 11, near Wytheville.

...U.S. Rt. 11, from M.P. 167 to M.P. 175.
...Interstate 64, from Lexington-Buena Vista to Staunton.

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Interstates that Interstate 81 crosses in Virginia.

Interstate 381, at Bristol.

The first BGS on NB I-81.

NB I-81 near I-381.

NB I-81 at I-381.
Interstate 77, at Wytheville.

NB I-81 near I-77.

BGS for I-77 on NB I-81.

NB I-81 near I-77.

NB I-81 at I-77 in Wytheville.
Interstate 77, near Fort Criswell.
Interstate 581, near Hollins.
Interstate 64, near Lexington.
Interstate 64, near Stauton.

EB I-64/NB I-81 one mile from east I-64. (April, 2025)

EB I-64/NB I-81 at east I-64. (April, 2025)
Interstate 66, near Strasburg.

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Branches of I-81 in Virginia.

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NB I-81 near the Tennessee/Virginia State Line.

NB I-81 in Bristol.

BGS for I-81 on NB I-381 in Bristol.

NB I-81 east of Bristol.

Mileage sign on NB I-81.

NB I-81 in Smyth County.

NB I-81 near Marion.

NB I-81 at a message board near Wytheville.

NB I-81 near Wytheville.

NB I-81 near U.S. Rt. 52 at Wytheville.

NB I-81/SB I-77/NB U.S. Rt. 11/SB U.S. Rt. 52 at Wytheville.

A guide marker for I-81/77 east of Wytheville.

A guide marker on SB U.S. Rt. 11.

A BGS on SB VA St Rt 262, southeast of Staunton.

EB I-64/NB I-81 north of VA St Rt 262, southeast of Staunton.

A BGS on WB I-64.

A BGS on NB I-81.

NB I-81 north of U.S. Rt. 250.

NB I-81 near Mt. Sidney.

NB I-81 south of VA St Rt 256.

NB I-81 north of VA St Rt 256.

NB I-81 at the Augusta/Rockingham County Line.

NB I-81 near Mt. Crawford.

NB I-81 at U.S. Rt. 11, near Dayton.

NB I-81 south of VA St Rt 253.

NB I-81 south of U.S. Rt. 33.

NB I-81 at U.S. Rt. 33.

NB I-81 at the Rockingham County/City of Harrisonburg Line.

NB I-81 north of Harrisonburg.

NB I-81 at Lacey Spring.

NB I_81 near New Market.

NB I-81 south of U.S. Rt. 211.

NB I-81 south of New Market.

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8 December 2025