Virginia State Route 381 is a short route connecting the center of Bristol to Interstate 81. This runs for aproimatly 2 miles. VA St Rt 381 passes through the following town in Washington County. Bristol
VA St Rt 381 is not multi-plexed in Washington County. VA St Rt 381 intersects the following highways in Washington County. Interstate 381, at Bristol. U.S. Rt. 11, at Bristol. U.S. Rt. 421, at Bristol. U.S. Rt. 19, at Bristol.