West Virginia State Route 25 is a north-south highway along the Kanawha River. This highway starts on the northside of Charleston and runs between the Kanawha River and Interstate 64 most of the way to the Kanawha/Putnam County Line. WV St Rt 25 intersects the following highways in Kanawha County. Charleston Dunbar Institute Nitro WV St Rt 25 is not multi-plexed in Kanawha County. WV St Rt 25 intersects the following highways in Kanawha County. U.S. Rt. 60, at Charleston. West Virginia State Route 62, at Charleston. West Virginia State Route 622, near Cross Lanes. Interstate 64, near Nitro.