West Virginia State Route 601 is a north-south highway runing mostly thorugh South Charleston. WV St Rt 601 passes through the following towns in Kanawha County. South Charleston Charleston WV St Rt 601 is not multi-plexed in Kanawha County. WV St Rt 601 intersects the following highways in Kanawha County. Interstate 64, at South Charleston. U.S. Rt. 60, at South Charleston. U.S. Rt. 119, at Charleston.