U.S. Federal Route 250 is a north-south highway in Southwestern Ohio County. From Wheeling south to the Ohio/Marshall County Line this is on a expressway. U.S. Rt. 250 passes thorugh the following town in Ohio County. Wheeling U.S. Rt. 250 is multi-plexed in Ohio County. Interstate 70, at Wheeling. U.S. Rt. 40, at Wheeling. West Virginia State Route 2, from Wheeling to the Ohio/Marshall County Line. U.S. Rt. 250 intersects the following highways in Ohio County. U.S. Rt. 40, at Wheeling. U.S. Rt. 40, at Wheeling. West Virginia State Route 2, at Wheeling. Interstate 70, at Wheeling. West Virginia State Route 2, at Wheeling.
NB U.S. Rt. 250/WV St Rt 2 at the Ohio/Marshall County Line. NB U.S. Rt. 250/WV St Rt 2 near 41st Street. NB U.S. Rt. 250/WV St Rt 2 south of I-470. NB U.S. Rt. 250/WV St Rt 2 at I-470. A BGS on EB I-470. This is actually in Ohio. NB U.S. Rt. 250/WV St Rt 2 north I-470. NB U.S. Rt. 250/WV St Rt 2 south of Wheeling Creek. NB U.S. Rt. 250/WV St Rt 2 at north WV St Rt 2. A BGS on WB I-70. WB I-70/NB U.S. Rt. 250 at Wheeling Tunnel. WB I-70/NB U.S. Rt. 250 in Wheeling Tunnel. WB I-70/NB U.S. Rt. 250 at north WV St Rt 2. WB I-70/NB U.S. Rt. 250 west of north WV St Rt 2. WB I-70/U.S. Rt. 40; NB U.S. Rt. 250 at the Ohio River. WB I-70/U.S. Rt. 40; NB U.S. Rt. 250 at the Ohio River. A BGS on WB I-70/NB U.S. Rt. 250. A BGS on WB I-70/NB U.S. Rt. 250.
