U.S. Federal Route 45 runs north-south through the center of Champaign County. This is the main north-south surface route through the Champaign-Urbana Metro area. U.S. Rt. 45 passes through the following towns in Champiagn County. Rantoul
Thomasboro
Urbana
Champaign
Savoy
Tolono Pesotum
U.S.Rt. 45 is multi-plexed in Champaign County. U.S. Rt. 150, at Urbana.
U.S. Rt. 45 intersects the following highways in Champaign County. U.S. Rt. 136, at Rantoul.
SB U.S. Rt. 45 at the Champaign/Ford County Line. SB U.S. Rt. 45 north of Rantoul. SB U.S. Rt. 45 in Rantoul. A Champaign County mile marker. SB U.S. Rt. 45 in Thomasboro. A old junction marker near Thomasboro. SB U.S. Rt. 45 north of I-74 in Urbana. A BGS on EB I-74. NB U.S. Rt. 45/EB U.S. Rt. 150 near the Universtiy of Illinois. A set of guide markers in Champaign. A older shield in Champaign. NB U.S. Rt. 45 in Savoy. NB U.S. Rt. 45 at Airport Road in Savoy. NB U.S. Rt. 45 near Willard Airport south of Savoy. NB U.S. Rt. 45 in Tolono. SB U.S. Rt. 45 near I-57 in Pesotum. A BGS on SB I-57. SB U.S. Rt. 45 south of I-57, south of Pesotum.