Roads of the Mid-South & West > Highways of the State of Illinois > Double Number U.S. Federal Highways of Illinois > U.S. Federal Route 45, Illinois > U.S. Federal Route 45; Cook County, Illinois

U.S. Federal Route 45
Cook County

U.S. Federal Route 45 is a north-south highway in Cook County. This is one of the longest counties that this highways passes through while in Illinois. It is one of the busiest north-south surface highways in this part of the county.

U.S. Rt. 45 passes through the following towns in Cook County.
Tinley Park

Orland Hills

Orland Park

Palos Park

Willow Springs

Hodgkins
Countryside
La Grange
La Grange Park
Westchester
Hillside

Bellwood
Melrose Park

Stone Park

Northlake

Franklin Park

Schiller Park

Rosemont

Des Plaines

Mount Prospect

Prospect Heights

Wheeling


U.S. Rt. 45 is multi-plexed in Cook County.
U.S. Rt. 12, from near Hickory Hills to Des Plaines.

U.S. Rt. 20, from near Hickory Hills to Stones Park.

Illinois State Route 21, from Prospect Heights to the Cook/Lake County Line.


U.S. Rt. 45 crosses the following highways in Cook County.
U.S. Rt. 6, at Orland Park.

Illinois State Route 7, at Orland Park. (NO DIRECT INTERSECTION)
Illinois State Route 83, near Palos Hills.
U.S. Rt. 12, near Hickory Hills.
U.S. Rt. 20, near Hickory Hills.

Illinois State Route 171, at Willow Springs.
Interstate 294, (Tri-State Tollway) at Willow Springs.
Interstate 55, (Stevenson Expressway) at Hodgkins.

U.S. Rt. 34, at La Grange.
Illinois State Route 38, at Westchester.
Interstate 290, (Dwight D. Eisenhower Expressway) at Hillside.
Illinois State Route 110, (Dwight D. Eisenhower Expressway) at Hillside.
Illinois State Route 56, at Bellwood.
U.S. Rt. 20, at Stones Park.

Illinois State Route 64, at Stones Park.
Interstate 294, (Tri-State Tollway) at Schiller Park. (NO INTERCHANGE)
Illinois State Route 19, at Schiller Park.
Interstate 190, (John F. Kennedy Expressway) at O'Hare International Airport.
Illinois State Route 72, at Des Plaines.
Interstate 90, (Northwest Tollway) at Des Plaines.
U.S. Rt. 14, at Des Plaines.
U.S. Rt. 12, at Des Plaines.
Illinois State Route 58, at Des Plaines.
Illinois State Route 21, at Prospect Heights.
Illinois State Route 68, at Wheeling.


NB U.S. Rt. 45/IL St Rt 21 in Wheeling.

A junction marker on EB IL St Rt 68.

A set of BGS's on EB I-190.

EB U.S. Rt. 12/SB U.S. Rt. 45 at O'Hare International Airport.

A guide marker in Franklin Park.

A guide marker in Franklin Park.

EB U.S. Rt. 12/SB U.S. Rt. 45 near Wrightwood in Franklin Park.

EB U.S. Rt. 12/SB U.S. Rt. 45 near Fullerton in Franklin Park.

NB U.S. Rt. 12/45 in Melrose Park.

NB U.S. Rt. 12/45 near IL St Rt 64.

A junction marker on EB IL St Rt 64.

A junction marker on EB U.S. Rt. 20.

A street sign on a stop light mast in Melrose Park.

A BGS on EB I-290.

A BGS on EB I-290.

A junction marker on EB IL St Rt 38.

EB U.S. Rt. 12/20; SB U.S. Rt. 45 in La Grange Park.

A junction marker on EB U.S. Rt. 34.

A set of guide markers on EB U.S. Rt. 34.

EB U.S. Rt. 12/20; SB U.S. Rt. 45 north of I-55.

A BGS on NB I-55.

Another BGS on NB I-55.

EB U.S. Rt. 12/20; NB U.S. Rt. 45 in Willow Springs.

A BGS on IL St Rt 171.

EB U.S. Rt. 12/20; SB U.S. Rt. 45 at I-294/IL St Rt 171.

NB U.S. Rt. 45 at the Cal-Sag Channel.

SB U.S. Rt. 45 in Palos Park.

NB U.S. Rt. 45 north of Southwest Highway.

A junction marker on EB U.S. Rt. 6.

NB U.S. Rt. 45 south of U.S. Rt. 6.

SB U.S. Rt. 45 at the Cook/Will County Line.

NB U.S. Rt. 45 at the Cook/Will County Line.

31 March 2017