U.S. Federal Route 45 runs north-south in Will County. Much of U.S. Rt. 45 is surrounded by farm land, with the exception of the area around the Will/Cook County Line. U.S. Rt. 45 passes through the following towns in Will County. Mokena
Frankfort
Andres
U.S. Rt. 45 is multi-plexed in Will County. U.S. Rt. 52, from 1 mile south of Andres to the Kankakee/Will County Line.
U.S. Rt. 45 intersects the following highways. Interstate 80, at Mokena. U.S. Rt. 30, at Frankfort.
NB U.S. Rt. 45/WB U.S. Rt. 52 at the Kankakee/Will County Line. Looking north at U.S. Rt. 45/52 at the Will/Kankakee County Line. SB U.S. Rt. 45/EB U.S. Rt. 52 south of Peotone Road. SB U.S. Rt. 45/EB U.S. Rt. 52 at Wilmington-Peotone Road. SB U.S. Rt. 45/EB U.S. Rt. 52 south of U.S. Rt. 52. (December, 2011) SB U.S. Rt. 45/EB U.S. Rt. 52 south of U.S. Rt. 52. (September, 2015) NB U.S. Rt. 45/WB U.S. Rt. 52 near Wilton Center. NB U.S. Rt. 45/EB U.S. Rt. 52 south of North Peotone Road. A junction marker on EB U.S. Rt. 52. A guide sign on EB U.S. Rt. 52. NB U.S. Rt. 45 north of U.S. Rt. 52. SB U.S. Rt. 45 near Andres. NB U.S. Rt. 45 south of Laraway Road. A guide marker on EB Laraway Road. NB U.S. Rt. 45 at the CN underpass. SB U.S. Rt. 45 in Frankfort. Ahead in the picture is a pedestrian walkway. NB U.S. Rt. 45 south of U.S. Rt. 30. A junction marker on EB U.S. Rt. 30. NB U.S. Rt. 45 at Colorado in Frankfort. NB U.S. Rt. 45 near 195th. NB U.S. Rt. 45 at I-80. A mileage chart on EB I-80 east of I-355. BGS on EB I-80. A BGS on EB I-80. A BGS on EB I-80. SB U.S. Rt. 45 south of the Cook/Will County Line. SB U.S. Rt. 45 at the Will/Cook County Line.
