U.S. Federal Route 35 runs along Interstate 70 in the East-Central portion of Wayne County. This highway connects teh northwestern corner of the county to the Greater-Richmond Area. U.S. Rt. 40 passes through the following towns in Wayne County. Economy Williamsburg U.S. Rt. 35 is multi-plexed in Wayne County. Indiana State Route 38, north of Richmond. Interstate 70, around Richmond.