Iowa State Route 2 is the main east-west highway in Central Lee County. This runs from the Mississippi River Bridge, at Fort Madison, to the Lee/Van Buren County Line, enar Farmington. IA St Rt 2 passes through the following towns in Lee County. Fort Madison
Donnelson
IA St Rt 2 is multi-plexed in Lee County. U.S. Rt. 61, at Fort Madison.
IA St Rt 2 intersects the following highways in Lee County. U.S. Rt. 61, at Fort Madison. U.S. Rt. 61, at Fort Madison.
The eastern end marker. A junction marker on SB U.S. Rt. 61. SB U.S. Rt. 61/WB IA St Rt 2 in Fort Madison. A BGS on SB U.S. Rt. 61/WB IA St Rt 2. WB IA St Rt 2 west of Ft. Madison. WB IA St Rt 2 at U.S. Rt. 218/IA St Rt 27. WB IA St Rt 2 west of Donnellson. WB IA St Rt 2 near the Van Buren/Lee County Line.