U.S. Federal Route 400 is a east-west highway in Central Sedgwick County. Through Wichita, this is a expressway. U.S. Rt. 400 passes through the following towns in Sedgwick County. Wichita Goddard U.S. Rt. 400 is multi-plexed in Sedgwick County. U.S. Rt. 54, through the county. U.S. Rt. 400 crosses through the following highways in Sedgwick County. Kansas State Route 96, at Wichita. Interstate 35, at Wichita. (NO DIRECT INTERCHANGE) Kansas Turnpike, at Wichita. (NO DIRECT INTERCHANGE) Interstate 135, at Wichita. U.S. Rt. 81, at Wichita. Kansas State Route 15, at Wichita. Interstate 235, at Wichita. Kansas State Route 163, near Garden Plain. Kansas State Route 251, near Cheney.