U.S. Federal Route 45 is the main north-south surface highway in Mc Cracken County. This is one of the main routes through Downtown Paducah. U.S. Rt. 45 passes through the following towns in Mc Cracken County. Paducah
Lone Oak
U.S. Rt. 45 is multi-plexed in Mc Cracken County. U.S. Rt. 60, at Paducah.
Branches of U.S. Rt. 45 SB U.S. Rt. 45 crossing the Ohio River. SB U.S. Rt. 45 crossing the Ohio River. SB U.S. Rt. 45 crossing the Ohio River. SB U.S. Rt. 45 crossing the Ohio River. SB U.S. Rt. 45 at the Kentucky Welcome Sign. SB U.S. Rt. 45 near 10th in Paducah. SB U.S. Rt. 45 at KY St Rt 305. SB U.S. Rt. 45 near Bob Noble Park. A junction marker on WB BUSN Loop I-24/BUSN U.S. Rt. 60. A set of guide markers on WB BUSN Loop I-24/BUSN U.S. Rt. 60. A guide marker on SB BUSN U.S. Rt. 45. SB U.S. Rt. 45/WB U.S. Rt. 62 near 31st. A guide marker on SB U.S. Rt. 45. SB U.S. Rt. 45 north I-24. A BGS on EB I-24. A BGS on EB I-24. A BGS on Jack Paxton Dr. A guide marker on Jack Paxton Dr. A BGS on a service road at I-24/U.S. Rt. 45. SB U.S. Rt. 45 south of I-24. SB U.S. Rt. 45 south of KY Sec St Rt 1322. SB U.S. Rt. 45 south of KY St Rt 339. SB U.S. Rt. 45 north of KY Sec St Rt 1241, near Lone Oak. SB U.S. Rt. 45 south of KY Sec St Rt 1241, near Lone Oak. SB U.S. Rt. 45 near Valiant Drive, south of Lone Oak. SB U.S. Rt. 45 south of KY Sec St Rt 1288. SB U.S. Rt. 45 near Colliersville Cemetery Road. SB U.S. Rt. 45 north of the Mc Cracken/Graves County Line.
