U.S. Federal Route 50 is an east-west highway in highway in Prince George's County. It runs from the Anne Arundel/Prince George's County Line, near Bowie, to the Washington D.C. line. U.S. Rt. 50 passes through the following town in Prince George's County. Bowie U.S. Rt. 50 is multi-plexed in Prince George's County. Interstate 595, from the Anne Arundel County Line to the Capital Beltway, near Seat Pleasant. U.S. Rt. 301, from the Anne/Arundel County Line to Bowie. U.S. Rt. 50 crosses the following highways in Prince George's County. U.S. Rt. 301, at Bowie.
WB U.S. Rt. 50 at the Anne Arundel/Prince George's County Line. WB I-595/U.S. Rt. 50 near MD St Rt 197. WB I-595/U.S. Rt. 50 at MD St Rt 197. WB I-595/U.S. Rt. 50 east of MD St Rt 704. WB I-595/U.S. Rt. 50 at MD St Rt 704. WB I-595/U.S. Rt. 50 west of MD St Rt 704. WB I-595/U.S. Rt. 50 at I-95/495. WB U.S. Rt. 50 at I-95/495. WB U.S. Rt. 50 west of I-95/495. WB U.S. Rt. 50 at MD St Rt 410. WB U.S. Rt. 50 east of MD St Rt 202. A BGS on NB MD St Rt 295. A BGS on NB MD St Rt 295. WB U.S. Rt. 50 west of MD St Rt 295. A guide sign on EB U.S. Rt. 50.