U.S. Federal Route 522 is a north-south highway in Western Washington County. It runs from the West Virginia/Maryland State Line, at Hancock, to the Pennsylvania/Maryland State Line, north of Hancock. This is just over two (2) miles in length within the State of Maryland. U.S. Rt. 522 passes through the following town in Washington County. Hancock U.S. Rt. 522 is multi-plexed in Washington County. Interstate 70, north of Hancock. U.S. Rt. 40, near Hancock. U.S. Rt. 522 intersects the following highways in Washington County. Maryland State Route 144, at Hancock. Interstate 70, near Hancock. U.S. Rt. 40, near Hancock. Interstate 68, near Hancock. U.S. Rt. 40, near Hancock.