Missouri Secondary State Route O is a short east-west highway in Pemiscot County. This highway is located in the south-central portion. MO Sec St Rt O does not pass through any towns in Pemiscot County. MO Sec St Rt O is not multi-plexed in Pemiscot County. MO Sec St Rt O intersects the following highways in Pemiscot County. U.S. Rt. 61, near State Line. Interstate 55, near State Line.
