Missouri State Route 19 is the main highway across Ralls County. It runs from near New London to the Audrain/Ralls County Line. MO St Rt 19 passes through the following town in Ralls County. Center MO St Rt 19 is multi-plexed in Ralls County. Missouri State Route 154, near Perry.
MO St Rt 19 intersects the following highways in Ralls County. U.S. Rt. 61, near New London.