Missouri State Route 366 runs east-west through the City of St. Louis. It runs alon Chippewa Ave. This is a former alignment of U.S. Rt. 66. MO St Rt 366 is not multi-plexed in the City of St. Louis. MO St Rt 366 intersects the following highways in the City of St. Louis. Missouri State Route 30, near Tower Grove Park.