Missouri State Route 51 is a north-south highway in Perry County. This is one of the main highways in the county. MO St Rt 51 also has the only Mississippi River crossing in the county, and area. The bridge over the Mississippi River, use to be a toll bridge, with a plaza on the Illinois side at Chester. MO St Rt. 51 passes through the following towns in Perry County. Mc Bride
MO St Rt 51 is not multi-plexed in Perry County. MO St Rt 51 intersects the following highways in Perry County. Missouri Secondary State Route C, near Mc Bride.