New York State Route 240 is a north-south highway in the Buffalo Metro Area. It runs from Amherst to the Erie/Cattaraugus County Line. NY St Rt 240 passes through the following towns in Erie County. Amherst Cheektowaga West Seneca Orchard Park Springville NY St Rt 240 is multi-plexed in Erie County. New York State Route 277, near Orchard Park. NY St Rt 277 crosses the following highways in Erie County. Interstate 290, at Amherst. New York State Route 324, at Amherst. New York State Route 5, at Amherst. New York State Route 33, near Cheektowaga. New York State Route 130, near Cheektowaga. New York State Route 354, near West Seneca. Interstate 90, (New York State Thruway), near West Seneca. New York State Route 400, near West Seneca. (NO Interchange) New York State Route 16, near West Seneca. New York State Route 277, near Orchard Park. U.S. Rt. 20, near Orchard Park. U.S. Rt. 20A, at Orchard Park. New York State Route 277, at Orchard Park. New York State Route 39, near Orchard Park.
