Ohio State Route 45 is a north-south highway in Western Ashtabula County. It goes from Ohio State Route 531, near Ashtabula, to the Ashtabula/Trumbull County Line. OH St Rt 45 passes through the following towns in Ashtabula County. Austinburg Rock Creek Rome Orwell OH St Rt 45 is not multi-plexed in Ashtabula County. OH St Rt 45 intersects the following highways in Ashtabula County. Ohio State Route 531, near Ashtabula. U.S. Rt. 20, near Saybrook. Ohio State Route 84, near Saybrook. Interstate 90, near Austinburg. Ohio State Route 307, at Austinburg. U.S. Rt. 6, at Rome. U.S. Rt. 322, at Orwell.
