Pennsylvania State Route 16 runs east-west across Southern Franklin County. It runs from the Adams/Franklin County Line, near Greenstone, to the Franklin/Fulton County Line, near Cove Gap. PA St Rt 16 passes through the following towns in Franklin County. Blue Ridge Summit Monterey Rouzerville Wayne Heights
WB PA St Rt 16 near the Franklin/Adams County Line. WB PA St Rt 16 west of Blue Ridge Summit. WB PA St Rt 16 west of Mentz Gap Road. WB PA St Rt 16 east of Recycle Center Road. WB PA St Rt 16 near Red Run. WB PA St Rt 16 east of Wayne Heights. WB PA St Rt 16 east of Old 16. WB PA St Rt 16 west of Old Forge Road. WB PA St Rt 16 east of 2nd St. WB PA St Rt 16 east of Enterprise St. WB PA St Rt 16/NB PA St Rt 997 west of Walnut Street. WB PA St Rt 16 west of Potomoc. WB PA St Rt 16 west of PA St Rt 316. WB PA St Rt 16 west of Waynesboro. WB PA St Rt 16 west of Waynesboro. WB PA St Rt 16 near Waynecastle. WB PA St Rt 16 at Shady Grove. WB PA St Rt 16 west of Shady Grove. WB PA St Rt 16 east of I-81. WB PA St Rt 16 west of I-81. WB PA St Rt 16 near Allison St. WB PA St Rt 16 east of Carlisle St. WB PA St Rt 16 east of Jefferson St. WB PA St Rt 16 west of U.S. Rt. 11. WB PA St Rt 16 west of Greencastle. WB PA St Rt 16 west of north PA St Rt 995. WB PA St Rt 16/SB PA St Rt 995 east of Upton. WB PA St Rt 16 west of south PA St Rt 995. WB PA St Rt 16/NB PA St Rt 416 east of Mercersburg. WB PA St Rt 16; NB PA St Rt 75/416 west of Constitution. WB PA St Rt 16; NB PA St Rt 75/416 north of Buchanan Trail West. WB PA St Rt 16; NB PA St Rt 75/416 south of Oregon. WB PA St Rt 16 west of Mercersburg. WB PA St Rt 16 near Charlestown. WB PA St Rt 16 east of Cove Gap. WB PA St Rt 16 at Cove Gap. WB PA St Rt 16 west of Cove Gap. WB PA St Rt 16 east of PA St Rt 456. WB PA St Rt 16 west of PA St Rt 456. WB PA St Rt 16 east of Fulton County.
