Pennsylvania State Route 381 is a north-south highway in Eastern Westmoreland County. It runs from the Fayette/Westmoreland County Line, near Champion, to U.S. Rt. 30, near Laughlintown. PA St Rt 381 passes through the following towns in Westmoreland County. Jones Mills Rector PA St Rt 381 is multi-plexed in Westmoreland County. Pennsylvania State Route 711, from the Fayette/Westmoreland County Line, to near Jones Mills. Pennsylvania State Route 31, near Jones Mills. PA St Rt 381 crosses the following highways in Westmoreland County. Pennsylvania State Route 31, near Jones Mills. Pennsylvania State Route 711, near Jones Mills. Pennsylvania State Route 31, at Jones Mills. Interstate 70, near Stahlstown. (NO Interchange) Interstate 76, near Stahlstown. (NO Interchange) Pennsylvania Turnpike, near Stahlstown. (NO Interchange) Pennsylvania State Route 130, near Stahlstown. U.S. Rt. 30, near Laughlintown.
